A new, multicenter, randomized trial showed transperineal biopsies had similar, if not slightly better, outcomes than the transrectal method. Medscape Medical News
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Author: Medscape
Adalimumab Tops Cyclosporine in Preventing Uveitis Relapse
Adalimumab was superior to cyclosporine in preventing uveitis relapse in patients with severe Behçet disease already on corticosteroid therapy, according to randomized, open-label trial results. Medscape Medical News
Cancer Risk: Are Pesticides the New Smoking?
Researchers found that pesticide exposure may contribute to 154.1% more non-Hodgkin lymphoma cases than smoking. Medscape Medical News
Five Steps to Improve Colonoscopy Performance
As quality indicators and benchmarks for colonoscopy increase in coming years, gastroenterologists must think about ways to improve performance across the procedure continuum. Medscape Medical News
Triptans Trump Newer, More Expensive Meds for Acute Migraine
The comparative efficacy and tolerability of oral migraine medications suggest four triptans are superior to the newer, more expensive migraine medications, new research showed. Medscape Medical News
New Endoscopic Method for GERD Diagnosis Shows High Accuracy
Assessing mucosal impedance via endoscopy could become the go-to method for diagnosing GERD, with high sensitivity and less patient discomfort. Medscape Medical News
United in Care: Nurses Lead Unionization Efforts
Nurses nationwide are advocating for themselves through unionization. Their demands? Better working conditions, increase in pay, and more admin support. Medscape Medical News
High-Dose Vitamin D Disappoints in Metastatic CRC: SOLARIS
High-dose vitamin D added to chemotherapy failed to provide a benefit in patients with metastatic colorectal cancer in the SOLARIS trial. Medscape Medical News
Heat-Related Deaths Surge in the United States Over 24 Years
A study found a 117% increase in the number of heat-related deaths in the United States from 1999 to 2023, with maximal deaths (2325 cases) recorded in 2023. Medscape Medical News
Hyperglycemia Linked to Mortality in Older Adults With T2D
Time spent above, not below, the target glucose range was associated with mortality in a study of adults with type 2 diabetes aged 75 years or older. Medscape Medical News
Is Europe Set Up for Equitable Access to Cancer Drugs?
Approval, reimbursement, and other factors make access to new cancer therapies complex. Medscape Medical News
Bariatric Surgery, Weight Loss Makes Brain Say Meh to Sweets
Sugary beverages were less satisfying to participants after bariatric surgery and weight loss, found a recent observational study that examined the neural correlates of sweet taste. Medscape Medical News
FDA OKs Adjuvant Ribociclib in Earlier Stage Breast Cancer
Unlike rival CDK 4/6 inhibitor abemaciclib, patients don’t need to be lymph-node positive to receive ribociclib after surgery. Medscape Medical News
Pembrolizumab Approved With Chemotherapy for MPM
The blockbuster PD-1 inhibitor now has indications across 21 malignancies. Medscape Medical News
Opt-Out Treatment Can Help Reluctant Smokers Quit Smoking
An opt-out treatment for tobacco use can be beneficial for people with low motivation to quit, showed the secondary analysis of a clinical trial. Medscape Medical News
Combining Semaglutide and Mineralocorticoids May Improve CKD
A FLOW subanalysis suggested the benefits of combination, but some questioned the rationale. Medscape Medical News
Fridays and Snacking Bad for Smart Insulin Pen Adherence
Poor adherence varies by day of week, age, and engagement with the connected pen/app. Medscape Medical News
Neurological Conditions Linked to Chronic Pelvic Pain
Patients with disabling pelvic pain may suffer for years with an undiagnosed neurological condition. Medscape Medical News
Roflumilast Cream Effective for AD in Phase 3 Studies
Treatment with roflumilast cream 0.15% once daily improved mild to moderate AD in two phase 3 randomized clinical trials of children 6 years or older and adults. Medscape Medical News
FIT Performance for CRC Screening Varies Widely
Commonly used fecal immunochemical tests vary in their performance, which has implications for the benefits and cost-effectiveness of FIT-based CRC screening programs. Medscape Medical News