‘Watershed Moment’: Semaglutide Effective in MASH

The GLP-1 receptor agonist improved both histology and fibrosis in patients, with additional improvements in their liver enzymes, noninvasive fibrosis markers, and cardiometabolic measurements. Medscape Medical News

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When Appendicitis Recurs: Two Case Studies

Stump appendicitis is a rare but serious complication often confused with other conditions, leading to delayed diagnosis and management. Medscape Medical News

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Examining T4/T3 Combination Therapy in Hypothyroidism

LT4 monotherapy remains the standard treatment for hypothyroidism, although a subset of patients continues to have hypothyroidism despite normal TSH and serum-free thyroxine levels. Medscape Medical News

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Elevated Stroke Risk Following NAION

Adults with nonarteritic anterior ischemic optic neuropathy have an increased risk for stroke over 10 years follow-up and could benefit from regular monitoring. Medscape Medical News

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For AF, LAA Rivals Anticoagulants After Ablation

For patients with atrial fibrillation who need protection from stroke and other complications after ablation, left atrial appendage closure rivaled oral anticoagulation in a randomized trial. Medscape Medical News

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Eliminate Clozapine REMS, FDA Panels Say

Two FDA panels were almost unanimous in their opinion that the agency should eliminate restrictions that psychiatrists and patients say limit access to clozapine. Medscape Medical News

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