Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Their findings are published in the journal Cell Reports Medicine.
- Health (80)
Category: Lifestyle
Latest Lifestyle news from the Middle East and around the world
New study examines educational disruptions for children
Children with special health care needs (CSHCN) often face significant disruptions in their education due to extended hospitalizations. A recent study published online in Disability and Rehabilitation on July 1, 2024, by a multidisciplinary team of Kessler Foundation and Children Specialized Hospital.
Breakthrough therapy heals spinal cord injuries
In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving “dancing molecules,” to repair tissues and reverse paralysis after severe spinal cord injuries.
Innovative dual-drug strategy for colorectal cancer treatment
A combination of two drugs was capable of suppressing tumors in a non-conventional manner. Instead of inhibiting tumor cell division, as the most widely used medications do, the strategy consisted of hyperactivating oncogenic signaling by these cells to the point where they became stressed.
New biomarker helps determine the optimal treatment for colon cancer
Many people with stage II or III colon cancer receive additional, or adjuvant, chemotherapy following surgery. However, clinical trials have shown that this treatment doesn’t improve the chances of survival for every patient. A study published July 25th, 2024 in Cell Reports Medicine identifies and validates a 10-gene biomarker that potentially predicts whether a stage II or III colon cancer patient will benefit from adjuvant chemotherapy.
Inflammation may not be key to fighting liver fibrosis in MAFLD
Researchers at UCLA Health uncovered new information about the role inflammation plays in mitigating liver fibrosis, which is associated with metabolic-associated fatty liver disease (MAFLD), one of the most common diseases in the world affecting up to 40 percent of U.S. adults. While inflammation in the liver has long been considered a prerequisite to developing liver fibrosis, the scarring and thickening of tissue that can impair the liver’s ability to function, this new research suggests that reducing inflammation may not influence the extent of fibrosis.
Unraveling the microbial dynamics of spontaneous fermentation
Shibazuke is a traditional Japanese eggplant pickle produced by the process of fermentation using lactic acid bacteria (LAB). LAB which is commonly present in vegetables causes the spontaneous fermentation of vegetables, resulting in the distinctive acidic flavor of pickles. While LAB is beneficial, other species of bacteria and microbes that may be present in the food source can affect the food quality and safety. Advancements in the areas of food technology and nutrition have allowed the large-scale fermentation of pickles via industrial fermenters, where conditions that affect fermentation like temperature, pH-acid levels, and salt content are closely monitored.
New study highlights paternal influence on child's T1D risk
New research to be presented at this year’s Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) shows that a child is almost twice as likely to develop type 1 diabetes (T1D) if their father has the condition than if their mother has the condition.
New guidelines expand BRCA testing and screening for men
More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women.
Study finds stark differences in stroke center access by income
Low-income communities are up to 42% less likely to obtain stroke center certification.
These Are The 3 Most Delusional Zodiac Signs—In Case You Were Wondering
Plus, the three signs most grounded in reality.
Compounded Semaglutide Overdoses Tied to Hospitalizations
The US Food and Drug Administration alerted clinicians, compounders, and patients about adverse events related to compounded semaglutide dosing errors. Medscape Medical News
Tick-Borne Illnesses Are on the Rise in Canada
Especially in the summer, medical professionals should keep an eye out for cases of Lyme disease, anaplasmosis, babesiosis, and Powassan virus, experts urged. Medscape Medical News
Here’s the Olympic Sport You Should Watch, Based on Your Zodiac Sign
Let the games begin!
EMA Says Don't Mix Mysimba and Opioid-Containing Meds
Existing advice for prescribing the weight loss drugs needs to be strengthened to minimize the risks from interactions, the European drug authority said. Medscape Medical News
The Simplest Way to Tell if Your Farm-Fresh Eggs Are Still Actually Fresh, According to a Chicken Farmer
Do your eggs sink or swim? We’re cracking the code on egg freshness!
14 At-Home Chemical Peels That’ll Brighten Your Skin Over Time
Chemical peels have come a long way from the formulas that require a pro’s hand or several days of downtime. Some of the best chemical peels pack in exfoliating acids that quickly and gently smooth away dead skin and brighten dark spots—all without irritation. The best part? Many of them are bottled to be safe […]
EU Backs Drug to Relieve Itching in Alagille Syndrome
The European Medicines Agency said there were exceptional circumstances for approving Kayfanda to treat pruritus in patients with the rare genetic disorder. Medscape Medical News
Anzupgo Approved in Europe for Severe Hand Eczema
The drug downregulates immune and inflammatory responses in cells linked to the disease pathology. Medscape Medical News
Take an Inside Look at the Olympic Track Spikes Team USA’s Fastest Runners Are Wearing in Paris
There’s a science behind the speed.
FDA Approves JAK Inhibitor for Alopecia Areata
The pivotal phase 3 trials enrolled 1223 adults in the United States, Canada, and Europe. Medscape Medical News
EMA Refuses Marketing Authorization for Alzheimer's Drug
Leqembi’s EU-wide marketing authorization was refused because the drug’s effect on delaying cognitive decline does not counterbalance the risk for serious adverse events. Medscape Medical News
EMA Backs Oral Drug for Primary Biliary Cholangitis
Iqirvo can delay liver fibrosis and cirrhosis in patients with primary biliary cholangitis, the European Medicines Agency decided. Medscape Medical News
Tirbanibulin 1% Safe in Extensive Actinic Keratosis
The safety and tolerability of tirbanibulin 1% in patients with actinic keratosis over a larger treatment field was confirmed in a phase 3 study. Medscape Medical News
Statins, Vitamin D, and Exercise in Older Adults
Mengru Wang, MD, reviews several recently published articles and guidelines relevant to the care of older adults in primary care. MDedge News
Cardiovascular Outcomes Better With Home Hemodialysis
Home hemodialysis was linked to reduced cardiovascular risks vs peritoneal dialysis in a large study, but key caveats were noted. Medscape Medical News
Jasmine Tea Doesn’t Just Smell Like Bliss—It’s Also Beneficial for Your Gut, Mood, and Skin
But how does it compare to green tea?
Never Smokers Turn to Vaping as Numbers Soar
Never smokers are taking up vaping. Medscape News UK
Heat Waves: A Silent Threat to Older Adults' Kidneys
Extreme exposure to dry and hot weather conditions increased the plasma creatinine and cystatin C levels in older adults, while young adults showed minor changes. Medscape Medical News
OK TMI: Why Can I Smell Myself Through My Pants?
Tight leggings aren’t always to blame for odor “down there.”
Phenotypic Shift, Varied Vasculopathy Noted in IPAH
Diffusion capacity of the lungs for carbon monoxide was a distinguishing factor in a new study. Medscape Medical News
The 9 Best at-Home Laser Hair Removal Devices, According to Dermatologists
Plus everything you need to know for an easy, breezy at-home hair removal experience.
Eco-Anxiety and Patients' Need for Mental Health Support
The effects of climate change are evident, but their consequences for mental health are not the same for everyone. Medscape Medical News
Which Patients With Early TNBC Can Avoid Chemotherapy?
Stromal tumor-infiltrating lymphocyte levels may help determine which patients with stage I TNBC can skip chemotherapy, findings from a recent registry analysis suggested. Medscape Medical News
Crepey Skin, Dark Spots, or Fine Lines On The Neck? 15 Firming Products To Help
Tech neck, begone.
My Body Feels So Much Stronger Than It Did 2 Weeks Ago — Here’s What I Did Differently
I feel so much stronger than I did two weeks ago.
'Doesn't Fit Anything I Trained for': Treating Chronic Lyme
Researchers, clinicians, and patient advocates at a national meeting weighed in on efforts needed to accelerate research on treatments for chronic illness associated with Lyme disease. Medscape Medical News
Sugar May Drive Dementia, German Medical Societies Warn
High blood sugar levels damage brain blood vessels and promote deposits on the vessel walls, thus reducing blood flow and nutrient supply to brain cells. Medscape Medical News
Inappropriate NSAID Prescribing Causing Avoidable Harm
Prescribing NSAIDs to people at high risk of harm from them has cost more than 6000 years of good health and £31 million for the NHS over the past decade, a study found. Medscape News UK
Poverty Causally Linked to Mental Illness and Vice Versa
There is a bidirectional, causal relationship between mental illness and poverty, new research shows. Medscape Medical News
7 Telltale Signs Of A “Type A” Personality, From Psychology Experts
Plus how it’s different from type B, C, and D.
This Plumping Cream Brightens My Dark Under-Eyes Better Than Any I’ve Tried
My entire face perked up.
23 Second Date Ideas To Actually Spark Connection, From Dating Experts
The key is to follow up on what you learned on the first date.
The Pros Tell All: The Key To Choosing A Lip Color That Complements Your Skin
Remember—makeup is an art, not a science.
My Complexion Looks Its Best When I'm Eating These 3 Delicious Foods
Food is skin care.
Is Mirror-Touch Synesthesia Real? The Pain and Pleasure of Physical Empathy
Mirror-touch synesthesia mimics the sensation of pain, pleasure, and everything in between.
Of All 12 Zodiac Signs, This One Is The Most Stubborn Of All
Ranked from most to least stubborn.
What Is Hyperphantasia? How to Tell If You Have an Extremely Vivid Imagination
Are you part of the three percent of the population who experience extreme hyperphantasia?
Coco Gauff Is an Olympic Flag Bearer—Here Are 5 Things to Know About the Tennis Phenom
You go, Coco.
These Portable Compression Sleeves Bring My Sore, Achy Legs Back to Life During Marathon Training
Meet my new favorite recovery tool.
The Universal Standard Sample Sale Is Offering up to 90% Off On *Hundreds* of Summer-to-Fall Staples
The deals are dealing.
Glen Powell Got His Dog During a Breakup—Here Are 5 More Heartwarming Stories of How Pets Help Us Heal
Dogs, cats, bunnies—they all seem to know just what we need when times are tough.
New Study Reveals Tattoo Ink Contamination—How Concerned Should You Be?
Researchers found that even bottles labeled “sterile” contained potentially harmful bacteria. Here’s how to stay safe if you’re getting inked.
Skip the Sweaty Feet With These 7 Mesh Ballet Flats, All Under $150
Sheer perfection!
This High-Protein Take on TikTok’s ‘Scrambled Pancakes’ Trend Will Keep You Full All Morning
It’s chef-created and sure to be delicious.
4 Delicious, High-Fiber Snacks With Fruit That Secretly Upgrade Your Lunchbox Favorites
Give your tastebuds a walk down memory lane.
The 13 Best Highlighter Drops to Use for an All-Over, Radiant Glow
Determining the best highlighter format for you depends on your skin type and how intense or subtle you want your glow. Highlighter drops are superior to other formats for this reason: they allow you to customize just how much radiance you add to your makeup look — you can use one drop for a subtle […]
3 Signs Your VO2 Max Is Low & How To Raise It ASAP
The new and buzzy metric.
Froth Your Morning Joe Like a Pro With This (Deeply Discounted) Keurig Coffee Maker
Sure, Keurig machines are known for making fast, easy brews. But just because they’re basically countertop-sized coffee vending machines doesn’t mean you can’t get fancy with your Keurig drinks—and the Keurig K-Cafe Barista Bar Coffee Maker is out to prove that statement true. This powerful little machine has the ability to create hot or cold […]
Do *This* After A Workout To Avoid Back, Butt, & Chest Breakouts (No, Not A Shower)
Plus, what other testers say.
The Type Of Shoe A Foot Health Expert Is Begging You To Stop Wearing
When you picture a running shoe, what do you see?
23 of the Best Hype Songs From Olympians for Your Most Powerful Workout Playlist Ever
These tracks are guaranteed to get you pumped.
If You Rely On This To Poop, You May Be At Greater Risk Of Dementia
Here are safer ways to get things moving fast.
3 Underrated Ways To Boost Skin Firmness & Ease Wrinkles
When you think of habits that can help firm your skin, your mind probably goes right to your daily skin care routine. But don’t forget these habits.
3 Expert Tips To Avoid Wrinkles & Fine Lines While You Sleep
Sleeping is not just idle time.
Struggling With Hair Loss? Add This Quick Step To Your Routine
It’s quick & easy.
I Finally Discovered The Root Cause Of My Dry Skin & Redness — It Wasn’t At All What I Expected
Don’t miss this rare sale.
This Zodiac Sign Needs Excitement (& Passion) In Their Relationships
Probably not a good fit for Capricorns.
Found: A 5-Step Guide To Finding Your True Purpose In Life
How do you know if you’re on the right path?
A Daily Snack For Tighter, Brighter Skin From A Celebrity Esthetician
Tighter skin ahead.
This Is the First Olympics to (Finally!) Have a Nursery—Here’s a Look Inside
“[There’s] a lot of ‘Why did this take so long? This seems like something that we should have had.’”
6 Signs of Aggressive Communication—and How to Be More Assertive About Your Needs
You don’t always have to be in fight-or-flight mode.
Bloom’s New Energy Drinks Are the Latest Trendy Beverages to Contain Prebiotic Fibers, but Can They Really Help With Gut Health?
A dietitian weighs in.
6 Signs Your Passive Communication Style Is Holding You Back—and How to Ask for What You Need
Feeling unseen and unheard? You may need to tweak your communication style.
Feeling Gunky? These Are the Best Hair Products for Sweaty Scalps, According to Pros
Your scalp will thank you.
4 Surprising Things Olympic Sprinter Kendall Ellis Can’t Live Without
They’re not (just) running related.
15 Exfoliators for Dry Skin That’ll Smooth Your Face Without Irritation
Dry skin needs love, too.
I Checked My Ovarian Reserve From Home In 10 Minutes — Here's How
And it takes just 10 minutes.
This (on Sale) It Cosmetics Set Gives You a Flawless No-Makeup Look With Only 2 Products
As someone who likes to wear a little makeup but hates a lengthy application process, I’m constantly hunting for products that do more with less. Even the no-makeup-makeup look can turn into an eight-step routine if you’re using single-focus products. That’s where the IT Cosmetics Glow With Confidence Set 3-Piece Set comes in. It includes […]
Protein Shakes, Piña Coladas, and Crushed Ice for Days: This Portable Blender Just Became My Summer BFF (and It’s on Sale Right Now)
Blend on the go.