New trial aims to make rectal cancer more responsive to radiation

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

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Microplastics exposure linked to increased risk of chronic diseases

Tiny fragments of plastic have become ubiquitous in our environment and our bodies. Higher exposure to these microplastics, which can be inadvertently consumed or inhaled, is associated with a heightened prevalence of chronic noncommunicable diseases, according to new research being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25).

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Increased mobility linked to lower risk of hospitalization in heart failure patients

Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a study being presented at the American College of Cardiology’s Annual Scientific Session (ACC.25).

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Waist Circumference Predicts Obesity-Related Cancer in Men

Findings of a study comparing waist circumference to BMI for predicting the development of obesity-related cancers show that waist circumference is a stronger risk marker in men but not in women. Medscape Medical News

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Neurology Patient Frailty: A Clinician's Guide

Frailty is a complex syndrome that may be under-recognized yet can complicate the clinical trajectory of neurologic diseases like dementia, Parkinson’s, multiple sclerosis, and stroke. Medscape Medical News

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Routine Adrenal Testing Post-Prednisolone May Not Be Needed

Only 1.9% of patients show glucocorticoid-induced adrenal insufficiency after discontinuing prednisolone, indicating that routine adrenal function testing with a short corticotropin test is unnecessary. Medscape News UK

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Nutrition Therapy Useful for Alcohol-Related ACLF

Dietitian-supported intensive nutritional therapy improves survival and disease severity in patients with alcohol-related acute-on-chronic liver failure, a study finds. Medscape Medical News

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Addressing Ageism in Rheumatology

Medscape Medical News speaks with Jiha Lee to discuss how to provide holistic, patient-centered care for older adults living with rheumatic disease. Medscape Medical News

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