Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.
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Rutgers researchers develop promising new oral antiviral for COVID-19
Rutgers Health researchers have developed an oral antiviral drug candidate for COVID-19 that could overcome major limitations of Paxlovid, currently the most prescribed oral treatment.
Updated screening protocols could improve early diagnosis of cystic fibrosis
All states should adopt updated screening protocols so more newborns with cystic fibrosis can be diagnosed in the first weeks of life, when interventions can have the greatest benefit, according to the Cystic Fibrosis Foundation guidelines published April 2 in the International Journal of Neonatal Screening.
Exercise helps retired adults combat mental fatigue
Retired people who habitually exercise are more able to fight the impacts of mental fatigue, new research suggests.
NIH trial demonstrates AI's effectiveness in opioid use disorder care
NIH-supported clinical trial shows AI tool as effective as healthcare providers in generating referrals to addiction specialists.
Smoothies with seeds may improve glycemic control, study shows
Blending whole fruits into smoothies may reduce glycemic spikes compared to eating fruit whole or drinking juice, especially when seeds are included. Researchers urge a re-evaluation of public health guidelines that currently limit smoothie intake.
Sweetener saccharin revives old antibiotics by breaking bacterial defences
Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits. The sweetener also re-sensitizes multidrug-resistant pathogens to antibiotics and disrupts stubborn biofilms.
Short on time? Weekend workouts still boost longevity, researchers say
A large UK Biobank study found that concentrating weekly physical activity into one or two days provides similar mortality benefits as spreading it across the week. Regular and “weekend warrior” exercise patterns both significantly reduced all-cause, cancer, and cardiovascular mortality.
Shingles vaccine cuts dementia risk by 20%, new study shows
A large natural experiment shows that the herpes zoster vaccine reduces dementia diagnoses by 20% over seven years. The findings suggest both viral suppression and immune training may play roles in brain health.
New thromboinflammation-on-a-chip model may revolutionize treatment of harmful blood clots
Blood clots are associated with life-threatening conditions such as sepsis, sickle cell disease, heart attack, and stroke.